ChatGPT says -
I’m not a medic, but the way these GLP-1/GIP drugs (like Mounjaro) work is a bit different from just “eating less = slower metabolism.”
Appetite suppression: Yes, you eat less, but the body doesn’t instantly crash your metabolism in the same way it would with crash dieting.
Hormonal effect: The meds mimic natural gut hormones, which not only reduce appetite but also influence blood sugar regulation, digestion speed, and satiety signalling. That seems to help preserve weight loss momentum even with lower intake.
Metabolism: There is usually some slowing of metabolic rate as body weight comes down (that happens with any weight loss), but the drugs aren’t thought to dramatically suppress metabolism beyond that normal adjustment.
Why it still works: The main driver is sustained adherence — people can keep in a calorie deficit without the constant hunger battle, which is normally where metabolism + appetite push back hardest.
So in short: metabolism may dip a bit as you lose weight, but the medication’s mechanism helps offset that by making the reduced intake manageable over the long term.