Bearing in mind that the actual number of total deaths per day from all causes is close to the top of that graph, it shows what a tiny percentage of deaths are being caused by coronavirus at present.cricketfieldclarets wrote: ↑Tue Jul 14, 2020 10:47 pmThey’ve included backdated figures from wales and the meat factories from several weeks ago.
This is the actual flow of things on dates things happened not dates they were added to reports. Makes a huge difference.
Covid-19
Re: Covid-19
-
- Been Liked: 1 time
- Has Liked: 944 times
Re: Covid-19
It's now 398 on the worldometers site https://www.worldometers.info/coronavirus/country/uk/cricketfieldclarets wrote: ↑Tue Jul 14, 2020 10:47 pmThey’ve included backdated figures from wales and the meat factories from several weeks ago.
This is the actual flow of things on dates things happened not dates they were added to reports. Makes a huge difference.
Seven day moving average has risen from 597 to 598 over the last seven days. Hardly a peak.
-
- Posts: 1313
- Joined: Fri Jul 21, 2017 8:12 pm
- Been Liked: 603 times
- Has Liked: 420 times
Re: Covid-19
New figures have indicated a significant rise in the Coronavirus cases attributed to Pendle, notably in Nelson and Brierfield.
https://www.lancs.live/news/lancashire- ... s-18597864
https://www.theboltonnews.co.uk/news/18 ... ion-rates/
It is a concern, but not a cause for immediate panic. However, following the advised safety protocols is in the best interests of everyone.
More worrying was this article
https://www.lancs.live/news/lancashire- ... 9-18586845
If that study is correct then the strategy for developing " Herd Immunity ", which is what we appear to have reverted to, will be untenable. The backbone of the " Herd Immunity " theory revolves around the natural development of antibodies in response to catching the virus. If natural antibodies decline at the rapid rate this study suggests they will only offer short term protection.
Stay sensible and stay safe
https://www.lancs.live/news/lancashire- ... s-18597864
https://www.theboltonnews.co.uk/news/18 ... ion-rates/
It is a concern, but not a cause for immediate panic. However, following the advised safety protocols is in the best interests of everyone.
More worrying was this article
https://www.lancs.live/news/lancashire- ... 9-18586845
If that study is correct then the strategy for developing " Herd Immunity ", which is what we appear to have reverted to, will be untenable. The backbone of the " Herd Immunity " theory revolves around the natural development of antibodies in response to catching the virus. If natural antibodies decline at the rapid rate this study suggests they will only offer short term protection.
Stay sensible and stay safe
-
- Posts: 21464
- Joined: Thu Jan 21, 2016 9:59 pm
- Been Liked: 8585 times
- Has Liked: 11285 times
Re: Covid-19
8 months into the pandemic and there hasnt been concrete proof of a single person being reinfected.Long Time Lurker wrote: ↑Wed Jul 15, 2020 9:16 amNew figures have indicated a significant rise in the Coronavirus cases attributed to Pendle, notably in Nelson and Brierfield.
https://www.lancs.live/news/lancashire- ... s-18597864
https://www.theboltonnews.co.uk/news/18 ... ion-rates/
It is a concern, but not a cause for immediate panic. However, following the advised safety protocols is in the best interests of everyone.
More worrying was this article
https://www.lancs.live/news/lancashire- ... 9-18586845
If that study is correct then the strategy for developing " Herd Immunity ", which is what we appear to have reverted to, will be untenable. The backbone of the " Herd Immunity " theory revolves around the natural development of antibodies in response to catching the virus. If natural antibodies decline at the rapid rate this study suggests they will only offer short term protection.
Stay sensible and stay safe
Re: Covid-19
As a child I was taught that the reason for immunity was that once you had had a disease, your body had learned to produce antibodies and would produce a load more at short notice if needed. Is that no longer accepted truth? Is the belief now that your body has to retain all the antibodies it has ever had?Long Time Lurker wrote: ↑Wed Jul 15, 2020 9:16 amIf that study is correct then the strategy for developing " Herd Immunity ", which is what we appear to have reverted to, will be untenable. The backbone of the " Herd Immunity " theory revolves around the natural development of antibodies in response to catching the virus. If natural antibodies decline at the rapid rate this study suggests they will only offer short term protection.
Stay sensible and stay safe
Easy enough for a scientist to check - count the measles antibodies, say in someone who had it twenty years ago vs. someone who had it last week. I'm sure it's been done - anyone know of a link?
Re: Covid-19
Clearest indication yet that we’ll be wearing masks in offices in a few weeks as Matt Hancock announces that there are no plans to make people wear masks in offices.
You could almost hear ‘the science changing’ as he was speaking!
You could almost hear ‘the science changing’ as he was speaking!
This user liked this post: FactualFrank
-
- Been Liked: 1 time
- Has Liked: 944 times
Re: Covid-19
I think you would need to compare over a whole season really. In the mid eighties crowds were as low as 5-6 thousand. In the early 90's, the attendance was 7-8 thousand on average. In the early noughties, with more or less the current ground, it was around 9-10 thousand. I would think that these matches would have provided a substantial proportion of the clubs income during these times.cricketfieldclarets wrote: ↑Tue Jul 14, 2020 1:10 pmWe played Sunderland this season in front of around 7,000 which is about 33% capacity. Pre Season even less fans usually. As are early league cup games which dont have the same following sunderland do.
I am sure all stands were open too.
I'm not sure how the 'cost of putting on a match' in the lower leagues in those times compares with the 'Premiership during a Pandemic'. I would think that they are now substantially higher.
If the club decided on such a course of action and chose the 'lucky 25%' (or perhaps 40%) from people who are less at risk from the virus, they would be selecting primarily young people. Teenagers would be first in the queue. Many of these would be paying the lower level concession ticket prices. On the other hand there would be no pensioner concessions attending.
-
- Posts: 1313
- Joined: Fri Jul 21, 2017 8:12 pm
- Been Liked: 603 times
- Has Liked: 420 times
Re: Covid-19
Sort of, it isn't just antibodies that contribute towards lasting immunity. T-cells play a major role, so a person with depleted antibodies could still fight off a new infection. Some repeat infection cases have been already been reported, but numbers are low. However, the relatively short time span of the pandemic ( impacted by lockdowns ) and the absence of full scale testing in some countries means the question is yet to receive a definitive answer. Studies are being conducted, but it is to early to say either way.dsr wrote: ↑Wed Jul 15, 2020 9:36 amAs a child I was taught that the reason for immunity was that once you had had a disease, your body had learned to produce antibodies and would produce a load more at short notice if needed. Is that no longer accepted truth? Is the belief now that your body has to retain all the antibodies it has ever had?
Easy enough for a scientist to check - count the measles antibodies, say in someone who had it twenty years ago vs. someone who had it last week. I'm sure it's been done - anyone know of a link?
Given that Science is playing catch up I can't see a problem with advocating a cautious and responsible approach to going about daily life. I mean what is the opposite outlook, a reckless and care free disregard for what are simple adjustments to how we conduct ourselves ?
-
- Been Liked: 1 time
- Has Liked: 944 times
Re: Covid-19
You're more or less right but it's not quite that simple. I'll try to explain.dsr wrote: ↑Wed Jul 15, 2020 9:36 amAs a child I was taught that the reason for immunity was that once you had had a disease, your body had learned to produce antibodies and would produce a load more at short notice if needed. Is that no longer accepted truth? Is the belief now that your body has to retain all the antibodies it has ever had?
Easy enough for a scientist to check - count the measles antibodies, say in someone who had it twenty years ago vs. someone who had it last week. I'm sure it's been done - anyone know of a link?
- Once your immune system overcomes a virus it produces antibodies and some kind of 'memory function' that enables it to recognise the virus and produce the antibodies should it encounter the infection again.
- Over the following months, if it does not encounter the virus again the body sheds the antibodies. However, it retains the memory.
- If the antibodies have gone the next time you encounter the infection you are reliant on your 'memory function'. Whilst the virus is multiplying within your 'receptor cells', the immune system is frantically searching for the correct 'memory cells' (or whatever they are) to produce the antibodies.
- When the 'memory function' finds the required stuff to produce the antibodies, billions of antibodies are produced to kill off the virus.
- If the viral load that the body receives is high (e.g. someone coughs near your face) the virus makes you sick before the 'memory function' can produce the antibodies to kill off the virus'. Eventually though the antibodies kill the virus.
- This is why you can catch a cold (some of which are coronavirus) in early winter and a second cold in later winter.
https://www.cbc.ca/news/health/asymptom ... -1.5629172
Not only are we learning people can contract the virus a second time, it's looking like a meaningful number of patients can get it even more times than that. And successive infections appear to have symptoms that are every bit as intense as the first.
Even among those who 'recover' -- even those cases that were asymptomatic -- numerous patients display long term organ damage (heart, lungs, kidneys, etc). https://www.youtube.com/watch?v=JfDpuouYUFc
Also.My patient caught Covid-19 twice. So long to herd immunity hopes?
https://www.vox.com/2020/7/12/21321653/ ... d-immunity
- Some viruses can go dormant in the body and re-emerge in a different form at a later time in life. Chickenpox-shingles is one example. Polio is another.
- Viruses can also transmute into different forms sometimes requiring the immune system to re-learn.
-
- Been Liked: 1 time
- Has Liked: 944 times
Re: Covid-19
Not good news for those who have had the virus without knowing it - and possibly younger people.
Newsweek
Coronavirus Damages Lungs of Asymptomatic Patients Too, Medical Examiner Says
Amedical examiner in Florida has warned that individuals who contract the novel coronavirus and are asymptomatic still appear to have lung damage.
"My gosh, I really don't know how to say it without being gruesome, it just destroys the lungs," Dr. Jon Thogmartin, the medical examiner for Pinellas and Pasco County said, WTVT-TV reported on Monday. "Let me just say that."
Thogmartin cited his own experience doing autopsies and a study published earlier this month by Scripps Research, a nonprofit medical research facility. That analysis suggested that up to 45 percent of those infected with the novel coronavirus were asymptomatic, while also noting that these individuals appeared to suffer lung damage.
"When the person dies, you can find lungs that don't look and feel like lungs anymore," Thogmartin said. https://www.newsweek.com/coronavirus-da ... ys-1514084
Re: Covid-19
In terms of infection rate Blackburn with Darwen lies second only to Leicester. This gives me another reason to avoid the place.
-
- Been Liked: 1 time
- Has Liked: 944 times
Re: Covid-19
"It is expected that supporters will be allowed to return to English league stadiums in some form from September"
https://www.theguardian.com/football/20 ... ext-season
https://www.theguardian.com/football/20 ... ext-season
Re: Covid-19
It’s exactly right that antibodies don’t need to be retained in the blood after an infection, it is memory B cells that circulate in the blood for up to 30 years after the initial infection. When these memory B cells encounter the pathogen for a second time, they immediately divide into plasma B cells which produce and secrete the antibody against the specific pathogen.dsr wrote: ↑Wed Jul 15, 2020 9:36 amAs a child I was taught that the reason for immunity was that once you had had a disease, your body had learned to produce antibodies and would produce a load more at short notice if needed. Is that no longer accepted truth? Is the belief now that your body has to retain all the antibodies it has ever had?
Easy enough for a scientist to check - count the measles antibodies, say in someone who had it twenty years ago vs. someone who had it last week. I'm sure it's been done - anyone know of a link?
I’ve seen a lot in the news about antibodies and T cells being the key to immunity, but I’ve seen very little mention of memory B cells. To my knowledge, these are the key to long term immunity.
-
- Been Liked: 1 time
- Has Liked: 944 times
Re: Covid-19
This chap is an example of re-infection.
Likely reinfected...when will this end
Tested Positive - Me
2.5 months in recovery almost all symptoms coming to a finish. Diagnosed positive at the ER and then tested negative for antibodies 7 weeks later. My coworker needed help driving and so I evaluated it low risk, it was just him and me in the car. I was in the car with him, no a/c, for ab 3 hours. Then 6 hours later my eyes are bright red and streaming tears just like in the first week of my covid battle. Runny nose too which I hadn't had since the first two weeks. Headache, some brain fog, and soar throat. Now I'm experiencing some chest pressure and small cough. This is a f*****g nightmare and all long termers need to be warned, do not listen to the govt or any news source. We will get it again, maybe not as bad but we are NOT immune. Be careful. I'm so defeated I don't want to do this anymore. It's horrible.
Re: Covid-19
Good luck sorting that one out, almost impossible I would suggest.UnderSeige wrote: ↑Wed Jul 15, 2020 11:25 am"It is expected that supporters will be allowed to return to English league stadiums in some form from September"
https://www.theguardian.com/football/20 ... ext-season
This user liked this post: UnderSeige
-
- Posts: 21464
- Joined: Thu Jan 21, 2016 9:59 pm
- Been Liked: 8585 times
- Has Liked: 11285 times
Re: Covid-19
Had heard this was quite likely. It had started to make an interesting debate on another thread. Positive news indeed.UnderSeige wrote: ↑Wed Jul 15, 2020 11:25 am"It is expected that supporters will be allowed to return to English league stadiums in some form from September"
https://www.theguardian.com/football/20 ... ext-season
This user liked this post: UnderSeige
-
- Been Liked: 1 time
- Has Liked: 944 times
Re: Covid-19
Coronavirus antibodies can start to fade away within weeks, according to a new study which puts a 'nail in the coffin' in the idea of herd immunity
King's College London research found that the presence of antibodies peaked three weeks after symptoms appeared, before fading away. It followed a Spanish study last week that also showed antibody protection rapidly declining in many patients. One of the UK study's authors said it put "another nail in the coffin of the dangerous concept of herd immunity." https://www.businessinsider.com/coronav ... ?r=US&IR=T
King's College London research found that the presence of antibodies peaked three weeks after symptoms appeared, before fading away. It followed a Spanish study last week that also showed antibody protection rapidly declining in many patients. One of the UK study's authors said it put "another nail in the coffin of the dangerous concept of herd immunity." https://www.businessinsider.com/coronav ... ?r=US&IR=T
-
- Posts: 21464
- Joined: Thu Jan 21, 2016 9:59 pm
- Been Liked: 8585 times
- Has Liked: 11285 times
Re: Covid-19
In the extremely unlikely event that there is no immunity we may as well crack on now then and get back to normalUnderSeige wrote: ↑Wed Jul 15, 2020 11:52 amCoronavirus antibodies can start to fade away within weeks, according to a new study which puts a 'nail in the coffin' in the idea of herd immunity
King's College London research found that the presence of antibodies peaked three weeks after symptoms appeared, before fading away. It followed a Spanish study last week that also showed antibody protection rapidly declining in many patients. One of the UK study's authors said it put "another nail in the coffin of the dangerous concept of herd immunity." https://www.businessinsider.com/coronav ... ?r=US&IR=T
-
- Posts: 21464
- Joined: Thu Jan 21, 2016 9:59 pm
- Been Liked: 8585 times
- Has Liked: 11285 times
Re: Covid-19
That's purely anecdotal. No hard evidence or across the board. 12m+ confirmed as infected. And how many confirmed as reinfected?
That one person is 0.000008333333333333334%
-
- Been Liked: 1 time
- Has Liked: 944 times
Re: Covid-19
The findings suggest one vaccine won't be enough
In an interview with Sky News reported by The Guardian, professor Robin Shattock of Imperial College London said that while reinfection would probably be "less severe" because of people retaining "immune memory," the risk of them passing on the virus meant they would likely have to receive boosts of the vaccine on a regular basis.https://www.businessinsider.com/coronav ... ?r=US&IR=T
-
- Been Liked: 1 time
- Has Liked: 944 times
Re: Covid-19
UK Prime Minister Boris Johnson's government has denied initially trying to pursue a strategy of herd immunity before it was warned that it would lead to the deaths of hundreds of thousands of people.
An Italian health minister last month said Johnson revealed his intention to pursue herd immunity in a phone call with Italian Prime Minister Giuseppe Conte on March 13, a little more than a week before the UK entered a countrywide lockdown.
On the same day, Patrick Vallance, the chief scientific adviser to the UK government, said he believed the UK would be able to achieve herd immunity.
https://www.businessinsider.com/coronav ... ?r=US&IR=T
-
- Been Liked: 1 time
- Has Liked: 944 times
Re: Covid-19
I think that it's one of those where we will have to watch this space and not be too positive of negative.cricketfieldclarets wrote: ↑Wed Jul 15, 2020 11:54 amThat's purely anecdotal. No hard evidence or across the board. 12m+ confirmed as infected. And how many confirmed as reinfected?
That one person is 0.000008333333333333334%
Rapid Loss of COVID-19 Antibodies
Kings College London StudyStudies Report Rapid Loss of COVID-19 Antibodies
The results, while preliminary, suggest that survivors of SARS-CoV-2 infection may be susceptible to reinfection within weeks or months. https://www.the-scientist.com/news-opin ... ies-67650
Covid-19 antibodies can decline over time, research suggests
Spanish study last week that also showed antibody protection rapidly declining in many patients.Immunity to Covid-19 could be lost in months, UK study suggests
Exclusive: King’s College London team found steep drops in patients’ antibody levels three months after infection https://www.theguardian.com/world/2020/ ... y-suggests
https://news.yahoo.com/coronavirus-herd ... 378.html [url]https://www.businessinsider.com/coronav ... ?r=US&IR=T[/url]
Doctor claiming that his patient caught COVID Twice
https://www.vox.com/2020/7/12/21321653/ ... d-immunity
WWE announcer Kayla Braxton says she had coronavirus twice
https://nypost.com/2020/06/25/wwe-annou ... us-twice/?
Woman tests positive for Covid-19 twice. Hear what she has to say.
https://edition.cnn.com/videos/health/2 ... tv-vpx.cnn
Here's another Anecdotal.
https://www.reddit.com/r/COVID19positiv ... einfected/
-
- Posts: 21464
- Joined: Thu Jan 21, 2016 9:59 pm
- Been Liked: 8585 times
- Has Liked: 11285 times
Re: Covid-19
In more positive news. Peer reviewed evidence that T cells play a major part in immunity both short and long term.
- Attachments
-
- 853D8A85-2834-41FD-8F83-3A4BC2C834A9.jpeg (679.59 KiB) Viewed 3198 times
Re: Covid-19
Despite the possibility of getting it twice it is likely that the second dose would be milder as our system would be more quickly gear up to attack the virus unless the next Covid-19 virus had mutated sufficiently to appear as a new type of infection to our immune system.
Some potential good news on the vaccine too.
From Mail on line on the Oxford vaccine with the lead researcher saying by September she is 80% confident we could have a vaccine. Theirs seems to be producing both an antibody and T cell response. T cells are the elephant in the immune system (they never forget) so it is possible the vaccine will work for several years at least
Some potential good news on the vaccine too.
From Mail on line on the Oxford vaccine with the lead researcher saying by September she is 80% confident we could have a vaccine. Theirs seems to be producing both an antibody and T cell response. T cells are the elephant in the immune system (they never forget) so it is possible the vaccine will work for several years at least
These 2 users liked this post: cricketfieldclarets tiger76
-
- Posts: 25445
- Joined: Sat Mar 26, 2016 12:46 am
- Been Liked: 6930 times
- Has Liked: 11660 times
- Location: Leeds
Re: Covid-19
You'll have to explain that one.cricketfieldclarets wrote: ↑Wed Jul 15, 2020 11:53 amIn the extremely unlikely event that there is no immunity we may as well crack on now then and get back to normal
-
- Posts: 21464
- Joined: Thu Jan 21, 2016 9:59 pm
- Been Liked: 8585 times
- Has Liked: 11285 times
Re: Covid-19
Excellent, positive news.mdd2 wrote: ↑Wed Jul 15, 2020 12:59 pmDespite the possibility of getting it twice it is likely that the second dose would be milder as our system would be more quickly gear up to attack the virus unless the next Covid-19 virus had mutated sufficiently to appear as a new type of infection to our immune system.
Some potential good news on the vaccine too.
From Mail on line on the Oxford vaccine with the lead researcher saying by September she is 80% confident we could have a vaccine. Theirs seems to be producing both an antibody and T cell response. T cells are the elephant in the immune system (they never forget) so it is possible the vaccine will work for several years at least
-
- Posts: 21464
- Joined: Thu Jan 21, 2016 9:59 pm
- Been Liked: 8585 times
- Has Liked: 11285 times
Re: Covid-19
The reality is that there is / will be some immunity. Its almost certain there will be.
But lets say there isnt. In that case its almost certain that a vaccine wont work. So we may as well let everyone out now.
But for clarity, I think there is / will be immunity and is / will be a succesful vaccine developed. So continuing to be sensible for now is the right approach.
-
- Posts: 25697
- Joined: Sat Jun 24, 2017 9:43 pm
- Been Liked: 4645 times
- Has Liked: 9849 times
- Location: Glasgow
Re: Covid-19
Scottish government daily briefing: Key points
There have been no Covid-19 deaths in preceding 24 hours for seventh day in row
Weekly NRS figures show 4,187 deaths now confirmed linked to Covid-19 which is up 13 - this includes deaths without a positive test
There were three days with no Covid admissions to hospital last week
Since 26 June, we've had six days in total where there have been no confirmed cases of the virus admitted to hospital.
The total number of deaths in Scotland from all causes last week was 56 below the five-year average. That's the third week in a row the total number of deaths has been below the five -year average.
Last week was the 11th week in a row that the number of deaths from Covid has fallen.
And only 5 new positive cases reported in Scotland today.
So amongst all the doom and gloom being spouted on this thread, there is plenty of good news to report.
There have been no Covid-19 deaths in preceding 24 hours for seventh day in row
Weekly NRS figures show 4,187 deaths now confirmed linked to Covid-19 which is up 13 - this includes deaths without a positive test
There were three days with no Covid admissions to hospital last week
Since 26 June, we've had six days in total where there have been no confirmed cases of the virus admitted to hospital.
The total number of deaths in Scotland from all causes last week was 56 below the five-year average. That's the third week in a row the total number of deaths has been below the five -year average.
Last week was the 11th week in a row that the number of deaths from Covid has fallen.
And only 5 new positive cases reported in Scotland today.
So amongst all the doom and gloom being spouted on this thread, there is plenty of good news to report.
This user liked this post: cricketfieldclarets
-
- Been Liked: 1 time
- Has Liked: 944 times
Re: Covid-19
If the vaccine will last for several years that is terrific news. The news that it could be ready by September is very old news but it's good to hear that they are still saying it. A few weeks ago I read that we should have a good idea about whether it will be ready in September/October by the end of July. It looks like we will know sometime in August now.mdd2 wrote: ↑Wed Jul 15, 2020 12:59 pmDespite the possibility of getting it twice it is likely that the second dose would be milder as our system would be more quickly gear up to attack the virus unless the next Covid-19 virus had mutated sufficiently to appear as a new type of infection to our immune system.
Some potential good news on the vaccine too.
From Mail on line on the Oxford vaccine with the lead researcher saying by September she is 80% confident we could have a vaccine. Theirs seems to be producing both an antibody and T cell response. T cells are the elephant in the immune system (they never forget) so it is possible the vaccine will work for several years at least
An article by Peston four hours ago says that : "I am hearing there will be positive news soon (perhaps tomorrow) on initial trials of the Oxford Covid-19 vaccine that is backed by AstraZeneca".... "That said, the efficacy will only be properly established in the large phase III programme that is under way in the viral epicentre of Brazil, to deliver a large database that assesses safety as well as efficacy". https://www.itv.com/news/2020-07-15/pos ... ert-pestonIt might be clear by the end of August whether or not the vaccine is effective. A single successful trial showing efficacy would allow a regulator to approve the vaccine for emergency use – something that would probably pave the way for use in high-risk groups. That could happen in October. https://inews.co.uk/news/science/corona ... als-497704
-
- Been Liked: 1 time
- Has Liked: 944 times
Re: Covid-19
It depends on the initial dose of the virus that you receive. A very small dose (e.g. by touching a virus infected surface) would take time to multiply. While that is going on the immune system (macrophage, t-cells, cytokins and eventually antibodies) would be alerted. It would then quickly smash the virus to pieces (in the back of the net).mdd2 wrote: ↑Wed Jul 15, 2020 12:59 pmDespite the possibility of getting it twice it is likely that the second dose would be milder as our system would be more quickly gear up to attack the virus unless the next Covid-19 virus had mutated sufficiently to appear as a new type of infection to our immune system.
Some potential good news on the vaccine too.
From Mail on line on the Oxford vaccine with the lead researcher saying by September she is 80% confident we could have a vaccine. Theirs seems to be producing both an antibody and T cell response. T cells are the elephant in the immune system (they never forget) so it is possible the vaccine will work for several years at least
On the other hand, if the initial dose is a high dose (e.g. breathing in millions of particles from the air where someone has just sneezed) the virus would already be at work before the immune system gets into gear. The patient becomes sick. However, you wouldn't expect it to last for weeks like it can on the first infection.
Re: Covid-19
Strange how our bodies have little immunity to a cold.cricketfieldclarets wrote: ↑Wed Jul 15, 2020 12:45 pmIn more positive news. Peer reviewed evidence that T cells play a major part in immunity both short and long term.
-
- Been Liked: 1 time
- Has Liked: 944 times
Re: Covid-19
The reality is that there is/will be full immunity eventually. If people are getting sick two or more times, as research is beginning to show, then herd immunity would take years if not decades without interventions.cricketfieldclarets wrote: ↑Wed Jul 15, 2020 1:59 pmThe reality is that there is / will be some immunity. Its almost certain there will be.
But lets say there isnt. In that case its almost certain that a vaccine wont work. So we may as well let everyone out now.
But for clarity, I think there is / will be immunity and is / will be a succesful vaccine developed. So continuing to be sensible for now is the right approach.
This doesn't mean that a vaccine won't work. It might mean however, that a repeat vaccine is required. If, for example the antibodies only last for three months, you would need a vaccine every three months. These early vaccines might not even stop you from getting sick. They will however greatly reduce the level of symptoms and speed up the recovery time at the very least (ask the monkeys in the Oxford trial).
Sometime next year the big companies (e.g. GSK) with decades of vaccine experience will likely be providing much stronger and longer lasting vaccines. They add an adjuvant (toxic material) to the vaccine which super alerts the immune system. They do this with flu vaccines. These are unlikely to be available until late next year.
The answer to letting everyone out now is USA and Brazil.
Stay realistically positive cricketfield. We could well be over the worst of it.
This user liked this post: FactualFrank
-
- Posts: 21464
- Joined: Thu Jan 21, 2016 9:59 pm
- Been Liked: 8585 times
- Has Liked: 11285 times
-
- Posts: 21464
- Joined: Thu Jan 21, 2016 9:59 pm
- Been Liked: 8585 times
- Has Liked: 11285 times
Re: Covid-19
Exactly. My point was if there's no immunity and no vaccine at all we may as well stop the lockdown. But both of those things are likely to be false.UnderSeige wrote: ↑Wed Jul 15, 2020 3:44 pmThe reality is that there is/will be full immunity eventually. If people are getting sick two or more times, as research is beginning to show, then herd immunity would take years if not decades without interventions.
This doesn't mean that a vaccine won't work. It might mean however, that a repeat vaccine is required. If, for example the antibodies only last for three months, you would need a vaccine every three months. These early vaccines might not even stop you from getting sick. They will however greatly reduce the level of symptoms and speed up the recovery time at the very least (ask the monkeys in the Oxford trial).
Sometime next year the big companies (e.g. GSK) with decades of vaccine experience will likely be providing much stronger and longer lasting vaccines. They add an adjuvant (toxic material) to the vaccine which super alerts the immune system. They do this with flu vaccines. These are unlikely to be available until late next year.
The answer to letting everyone out now is USA and Brazil.
Stay realistically positive cricketfield. We could well be over the worst of it.
I'm positive and optimistic. More so than ever. And avoiding the news and main stream media gives us all reason to be positive.
But we need to remain cautious, wary and sensible.
-
- Posts: 21464
- Joined: Thu Jan 21, 2016 9:59 pm
- Been Liked: 8585 times
- Has Liked: 11285 times
Re: Covid-19
Wednesday update




- Attachments
-
- Wednesday update.JPG (47.61 KiB) Viewed 3001 times
These 2 users liked this post: KateR bfcjg
Re: Covid-19
People get measles twice. I think we can be fairly sure that having coronavirus once does not give full immunity to everyone in the world against having it again. But from the very few apparent cases where it has happened, there is a very good chance that (like measles) you are immune to a second dose unless you're one of the very unlucky few.UnderSeige wrote: ↑Wed Jul 15, 2020 3:44 pmThe reality is that there is/will be full immunity eventually. If people are getting sick two or more times, as research is beginning to show, then herd immunity would take years if not decades without interventions.
This doesn't mean that a vaccine won't work. It might mean however, that a repeat vaccine is required. If, for example the antibodies only last for three months, you would need a vaccine every three months. These early vaccines might not even stop you from getting sick. They will however greatly reduce the level of symptoms and speed up the recovery time at the very least (ask the monkeys in the Oxford trial).
Sometime next year the big companies (e.g. GSK) with decades of vaccine experience will likely be providing much stronger and longer lasting vaccines. They add an adjuvant (toxic material) to the vaccine which super alerts the immune system. They do this with flu vaccines. These are unlikely to be available until late next year.
The answer to letting everyone out now is USA and Brazil.
Stay realistically positive cricketfield. We could well be over the worst of it.
Re: Covid-19
I think us over 50's will be getting a jab in October.
https://uk.news.yahoo.com/oxford-corona ... 09645.html
It was posted on here months ago that this one looks like a runner.
https://uk.news.yahoo.com/oxford-corona ... 09645.html
It was posted on here months ago that this one looks like a runner.
-
- Posts: 8842
- Joined: Thu Jan 21, 2016 5:22 pm
- Been Liked: 3020 times
- Has Liked: 1865 times
Re: Covid-19
might have been discussed on here, but why are we being asked to wear masks now, but pub goers do not have to.
in essence, they can occupy a bar, then leave and go to tesco where they are obliged to don a facemask.
in essence, they can occupy a bar, then leave and go to tesco where they are obliged to don a facemask.
-
- Posts: 21464
- Joined: Thu Jan 21, 2016 9:59 pm
- Been Liked: 8585 times
- Has Liked: 11285 times
Re: Covid-19
There was an explanation that wearing a mask in a setting like a supermarket where you briefly pass people will offer protection.Wile E Coyote wrote: ↑Thu Jul 16, 2020 12:22 ammight have been discussed on here, but why are we being asked to wear masks now, but pub goers do not have to.
in essence, they can occupy a bar, then leave and go to tesco where they are obliged to don a facemask.
But in a pub where you are sat for some time surrounded by people constantly the mask isnt effective.
How much truth is in that god knows.
The inconsistent messaging especially on masks has been the problem. I said right at the start that eventually they will enforce mask wearing. Just didn’t want to at the beginning when hospitals didn’t have enough.
Re: Covid-19
The problem is that if they are enforcing it now for coronavirus when it is a tiny risk, will they ever rescind the order? As we know, winter deaths are significantly higher because of flu and pneumonia. Will they tell us all winter long that we must wear these masks to stop the spread of flu?cricketfieldclarets wrote: ↑Thu Jul 16, 2020 12:31 amThere was an explanation that wearing a mask in a setting like a supermarket where you briefly pass people will offer protection.
But in a pub where you are sat for some time surrounded by people constantly the mask isnt effective.
How much truth is in that god knows.
The inconsistent messaging especially on masks has been the problem. I said right at the start that eventually they will enforce mask wearing. Just didn’t want to at the beginning when hospitals didn’t have enough.
-
- Posts: 21464
- Joined: Thu Jan 21, 2016 9:59 pm
- Been Liked: 8585 times
- Has Liked: 11285 times
Re: Covid-19
Not for flu. Because there is immunity to it and there is a vaccine for it.dsr wrote: ↑Thu Jul 16, 2020 12:40 amThe problem is that if they are enforcing it now for coronavirus when it is a tiny risk, will they ever rescind the order? As we know, winter deaths are significantly higher because of flu and pneumonia. Will they tell us all winter long that we must wear these masks to stop the spread of flu?
FWIW I think it’s a sensible step to take to prevent any upturn before winter. And also to give people confidence to go in shops.
Keeping it down while it’s very low has to be a good thing. Makes it even harder to spread and hopefully may see the back of it!
I’d sooner don a mask than go into lockdown.
For all saying it’s a ploy by the government etc. I can’t think of one good reason that they’d want to control us by enforcing masks. Especially when when it would be easier to control us via no masks and facial recognition!!
-
- Posts: 25445
- Joined: Sat Mar 26, 2016 12:46 am
- Been Liked: 6930 times
- Has Liked: 11660 times
- Location: Leeds
Re: Covid-19
Wearing a mask for my own and others' safety is ridiculous. In protest, tonight I will be driving up and down the M1 without a seatbelt or headlights on.
-
- Been Liked: 1 time
- Has Liked: 944 times
Re: Covid-19
I think that's the key to understanding the mask confusion. Government avoiding embarrassment of UK Mask shortage and not wanting the public to frantically buy masks like they did with toilet rolls and hand sanitiser.cricketfieldclarets wrote: ↑Thu Jul 16, 2020 12:31 amThe inconsistent messaging especially on masks has been the problem. I said right at the start that eventually they will enforce mask wearing. Just didn’t want to at the beginning when hospitals didn’t have enough.
I don't know why the government didn't just explain the situation and then, through the media, suggest ways of making masks and face coverings. They could have even presented mask making as a 'fun thing'.
-
- Posts: 21464
- Joined: Thu Jan 21, 2016 9:59 pm
- Been Liked: 8585 times
- Has Liked: 11285 times
-
- Posts: 25445
- Joined: Sat Mar 26, 2016 12:46 am
- Been Liked: 6930 times
- Has Liked: 11660 times
- Location: Leeds
Re: Covid-19
I always get worried when people mention 'game-changer'
-
- Been Liked: 1 time
- Has Liked: 944 times
Re: Covid-19
Possible but we don't know that yet. The reports are saying that the 'do nothing herd immunity approach' won't work or will at least take a number of years to work through. COVID-19 is not the measles.dsr wrote: ↑Wed Jul 15, 2020 5:16 pmPeople get measles twice. I think we can be fairly sure that having coronavirus once does not give full immunity to everyone in the world against having it again. But from the very few apparent cases where it has happened, there is a very good chance that (like measles) you are immune to a second dose unless you're one of the very unlucky few.
Researchers from Korea, Japan, China, Spain and now Kings College London, some of them using live human cases, are finding that antibodies are not retained for much longer than 3 months. As several of us discussed yesterday, the immune system is then reliant upon other weapons in it's arsenal (macrophage, T-cells, cytokins etc.)to fight off new infections until the memory cells can produce new antibodies.
A growing, but relatively small, number of people are now being found to have had COVID-19 twice (see posts from yesterday). How long would it take from the start of the pandemic before people started to get it twice.
- Serious numbers of cases started around mid March (Earlier for China).
- Recovery time - "The median time from onset to clinical recovery for mild cases is approximately 2 weeks and is 3-6 weeks for patients with severe or critical disease"(WHO). Takes us to early April (May for critical).
- After 3 months, many patients will have lost antibodies. Takes us to July (August for critical)Round about now.
- When have second cases started to come forward? Round about now.
-
- Been Liked: 1 time
- Has Liked: 944 times
Re: Covid-19
Let's hope so. On Peston last night Matt Hancock said that the 'best case scenario' is sometime this year and the likely scenario is next year. The scientist at Oxford and Astrazenica look to be saying that there is a 80% chance of it being successful and if successful, vaccinations will be starting in about ten weeks time.bfcjg wrote: ↑Wed Jul 15, 2020 10:48 pmI think us over 50's will be getting a jab in October.
https://uk.news.yahoo.com/oxford-corona ... 09645.html
It was posted on here months ago that this one looks like a runner.
My take on it all is that if it's successful we will have it in early October and if not, they will go back to work on it with a view to having it ready for next year. It's looking good at the moment.
Hancock also said that it will first be rolled out to the 'clinically vulnerable', 'the very old' and 'health workers''. Following this it will be applied down the age groups. He said the Distribution structures (GP's, chemists, work places etc) are already in place. He also said that pharmacies will be playing a big role.
This user liked this post: bfcjg